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Study of a High-Availability Dual Computer System with Fault Tolerant Architecture

Jin Shiyao,Hu Huaping,Li Hongliang

Strategic Study of CAE 1999, Volume 1, Issue 3, Pages 46-50

Abstract: there are great progresses in the analysis of availability, the judgement over of two results and the switch

Keywords： availability duplex system fault judgement ratio switch success ratio

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Low crosstalk switch unit for dense piezoelectric sensor networks

Lei QIU, Shenfang YUAN,

Frontiers of Mechanical Engineering 2009, Volume 4, Issue 4, Pages 401-406 doi: 10.1007/s11465-009-0047-4

Abstract: high sampling rate and limited quantity of signal amplifiers used in an integrated computer system, a switchunit is adopted to switch to different channels.high frequency and power of the lamb wave excitation signal, there exists a crosstalk signal in the switchThen a 24-switch channel low crosstalk switch unit based on a digital I/O board PCI7248 produced by AdlinkFinally, a general software program based on LabVIEW software platform is developed to control this switch

Keywords： structural health monitoring (SHM) piezoelectric (PZT) sensor networks switch unit crosstalk signal

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Identification of Critical Success Factors for Construction Innovation: From the Perspective of Strategic

Hui Liu,Meng-jun Wang,Miroslaw J. Skibniewski,Ji-shan He,Zhen-sen Zhang

Frontiers of Engineering Management 2014, Volume 1, Issue 2, Pages 202-209 doi: 10.15302/J-FEM-2014027

Abstract: Therefore, it is significant to explore the Critical Success Factors (CSFs) of construction innovation

Keywords： critical success factors construction innovation identification strategic cooperation

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Success criteria of large scale construction project based on system thinking

WangJin,Xu Yujie

Strategic Study of CAE 2008, Volume 10, Issue 12, Pages 79-85

Abstract: And it gives a comprehensive evaluation of the large scale project success from three perspectives of

Keywords： large scale construction project system thinking triple bottom line success criteria

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cells redirected against tumor-specific antigen glycoforms: can low-sugar antigens guarantee a sweet success

Frontiers of Medicine 2022, Volume 16, Issue 3, Pages 322-338 doi: 10.1007/s11684-021-0901-2

Abstract: Immune-based therapies have experienced a pronounced breakthrough in the past decades as they acquired multiple US Food and Drug Administration (FDA) approvals for various indications. To date, six chimeric antigen receptor T cell (CAR-T) therapies have been permitted for the treatment of certain patients with relapsed/refractory hematologic malignancies. However, several clinical trials of solid tumor CAR-T therapies were prematurely terminated, or they reported life-threatening treatment-related damages to healthy tissues. The simultaneous expression of target antigens by healthy organs and tumor cells is partly responsible for such toxicities. Alongside targeting tumor-specific antigens, targeting the aberrantly glycosylated glycoforms of tumor-associated antigens can also minimize the off-tumor effects of CAR-T therapies. Tn, T, and sialyl-Tn antigens have been reported to be involved in tumor progression and metastasis, and their expression results from the dysregulation of a series of glycosyltransferases and the endoplasmic reticulum protein chaperone, Cosmc. Moreover, these glycoforms have been associated with various types of cancers, including prostate, breast, colon, gastric, and lung cancers. Here, we discuss how underglycosylated antigens emerge and then detail the latest advances in the development of CAR-T-based immunotherapies that target some of such antigens.

Keywords： cancer immunotherapy chimeric antigen receptor solid tumors tumor-associated antigen glycosylation O-glycans adoptive cell therapy

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Hydraulic Pressure Extremes Ratio & Extremes Ratio Efficiencies

Qi Maolin

Strategic Study of CAE 2001, Volume 3, Issue 4, Pages 73-75

Abstract: applies basic formula to the calculation of a relationship between the hydraulic pressure extremes ratioof hydraulic system and the extremes ratio efficiencies.This relationship shows that the greater the hydraulic pressure extremes ratio is, the lower the extremesratio efficiencies are.The article holds that the hydraulic pressure extremes ratio can be designed and chosen.

Keywords： hydraulic pressure extremes ratio extremes ratio efficiencies hydraulic system

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Controlling interstory drift ratio profiles via topology optimization strategies

Frontiers of Structural and Civil Engineering 2023, Volume 17, Issue 2, Pages 165-178 doi: 10.1007/s11709-022-0892-3

Abstract: proposed approach involves solving a min–max optimization problem to suppress the maximum interstory drift ratioThe proposed methodology can shape the interstory drift ratio profiles into inverted triangular or quadratic

Keywords： interstory drift ratio aggregation function bound formulation min–max problem topology optimization

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Synthesis and properties of tetrathiafulvalene-porphyrin assemblies

Meijiang LI, Rui HUANG, Changzhi WU, Hujin ZUO, Guoqiao LAI, Yongjia SHEN

Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 4, Pages 422-428 doi: 10.1007/s11705-011-1124-x

Abstract: unit using chemical methods, which exhibited their potential application in fluorescence molecular switch

Keywords： tetrathiafulvalene tetraphenylporphyrin dyad triad fluorescence molecular switch

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The Development in Electrostatic Protection Engineering

Liu Shanghe,Tan Zhiliang,Wu Zhancheng

Strategic Study of CAE 2000, Volume 2, Issue 11, Pages 17-24

Abstract: The success and development in electrostatic protection engineering in China are introduced.

Keywords： Electrostatic hazards effect mechanism protection engineering success and development

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Generation and repair of AID-initiated DNA lesions in B lymphocytes

Zhangguo Chen,Jing H. Wang

Frontiers of Medicine 2014, Volume 8, Issue 2, Pages 201-216 doi: 10.1007/s11684-014-0324-4

Abstract: In mammalian B cells, this process includes somatic hypermutation (SHM) and class switch recombination

Keywords： class switch recombination somatic hypermutation activation-induced deaminase DNA repair genomic instability

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A methodology of implementing target mixing ratio for asphalt mixture

Yucheng HUANG, Lun JI, Rui WEN, Ming ZHANG

Frontiers of Structural and Civil Engineering 2017, Volume 11, Issue 3, Pages 308-314 doi: 10.1007/s11709-017-0405-y

Abstract: of hot mix asphalt adequately during the construction process, the significance of objective mixing ratioThe results show that the set of methods can not only implement the objective mixing ratio of hot mix

Keywords： asphalt mixture target mixing ratio mix design implementation batching & mixing plant debugging

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Diagnostic evaluation of plasma aldosterone concentration to plasma renin activity ratio in primary aldosteronism

ZHANG Huilan, WANG Daowen

Frontiers of Medicine 2008, Volume 2, Issue 1, Pages 11-14 doi: 10.1007/s11684-008-0003-4

Abstract: Using the plasma aldosterone concentration to plasma renin activity ratio (PAC/PRA ratio) as the screeninghypertensive patients, we studied the clinical characteristics and the diagnostic value of PAC/PRA ratioOne hundred and twenty-six suspected primary aldosteronism patients whose PAC/PRA ratio was > 25 ng/dLThe PAC/PRA ratio can be considered as a routine screening test in hypertensives, especially resistanthypertensive patients and a high PAC/PRA ratio is an invaluable index in primary aldosteronism diagnosis

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Enhancing the efficiency of nitrogen removing bacterial population to a wide range of C:N ratio (1.5:

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 8, doi: 10.1007/s11783-022-1522-y

Abstract:

• Simultaneous C & N removal in Methammox occurs at wide C:N ratio.

Keywords： Methanogens Biological Nitrogen Removal (BNR) Simultaneous Methammox C:N ratio

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Experimental study of structural damage identification based on modal parameters and decay ratio of acceleration

Zhigen WU, Guohua LIU, Zihua ZHANG

Frontiers of Structural and Civil Engineering 2011, Volume 5, Issue 1, Pages 112-120 doi: 10.1007/s11709-010-0069-3

Abstract: A novel damage assessment method based on the decay ratio of acceleration signals (DRAS) was proposed

Keywords： damage assessment decay ratio of acceleration signals (DRAS) wavelet transform (WT) modal analysis reinforced

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The influence of the NCO/OH ratio and the 1,6-hexanediol/dimethylol propionic acid molar ratio on the

Jiao Feng, Qiuhao Lu, Weimin Tan, Kequan Chen, Pingkai Ouyang

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 1, Pages 80-89 doi: 10.1007/s11705-018-1763-2

Abstract: indicate that the degree of hydrogen bonding and the numbers of urea groups increase as the NCO/OH ratioand HDO/DMPA molar ratio increase.Furthermore, the phase separation increases and the thermal stability decreases as the NCO/OH ratio increasesor the HDO/DMPA molar ratio decreases.

Keywords： 1 5-pentamethylene diisocyanate polyurethane water based